The Best OTC Proton Pump Inhibitor (PPI)

Oh boy, it’s time to do an introductory comparison of the three Proton Pump Inhibitors (PPIs) that are available over-the-counter. 

As of right now, you can get your hands on Zegerid OTC, Prilosec OTC, and Prevacid 24HR to treat your irritating and painful stomach ailment without having to get a prescription from your physician.  With this in mind, I thought it would be a genius idea to slip you a video that supplies the answer to the question I know you all have…which OTC PPI is the best to take?

The answer:

Sorry, guys!  I know you were looking for a better answer than that, but the truth really is one OTC PPI is not better than the other and they all have the same safety precautions/side effects.  It really does come down to the price tag and personal preference!

Agree? Disagree? Have some experience with OTC PPIs?  Leave a comment below or e-mail me at

While we’re at it, don’t forget to grab our FREE video course on how to save money on your prescription medications.  It’s instantly accessible and full of great ideas!

Have a great day!

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Thank you very much for your advice. I was confused, but now have some clarity about which PPI to choose.

Is Omeprezole with magnesium 20mg.equal to prilosec otc. or not?

Hi! Yes Prilosec’s generic is omeprazole magnesium. It works exactly the same.

Take care,

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